Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515221 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL25515216 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL25515219 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL25515231 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL25515232 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL25515220 | 1.00 | KDM4E (0.50) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL1645600 | 0.79 | NPC1 (0.47) | KDM4EALDH1A1MAPTPOLBALOX15 | |
| SCHEMBL25169307 | 0.75 | MAPT (0.38) | KDM4EALDH1A1MAPTPOLBALOX15 | |
| SCHEMBL25514619 | 0.75 | MAPT (0.40) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL17372792 | 0.75 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MAPTPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |