SCHEMBL25515696

SCHEMBL25515696

COc1ccc(C(=O)c2ccc3c(c2)c2ccccc2n3CCCn2c3ccccc3c3cc(C(=O)c4ccc(OC)cc4)ccc32)cc1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.68
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
SCARB1 Q8WTV0 1/20 0.53
CNR1 P21554 2/20 0.51
SLC6A1 P30531 1/20 0.51
SLC6A12 P48065 1/20 0.51
SLC6A11 P48066 1/20 0.51
SMPD1 P17405 1/20 0.50
TSPO P30536 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30000178 0.89 MAPT (0.60) CNR2ALDH1A1HPGDTSPO
SCHEMBL23781994 0.89 MAPT (0.60) CNR2ALDH1A1HPGDTSPO
SCHEMBL9459043 0.81 PTGER4 (0.55) CNR2ALDH1A1HPGD
SCHEMBL601022 0.81 CNR2 (1.00) CNR2ALDH1A1HPGDCNR1
SCHEMBL25515583 0.81 CNR2 (0.56) CNR2ALDH1A1HPGDCNR1TSPO
SCHEMBL23801739 0.77 KDM4E (0.50) CNR2ALDH1A1HPGD
SCHEMBL16510400 0.77 GCGR (0.53) CNR2ALDH1A1HPGDCNR1
SCHEMBL10579016 0.77 KDM4E (0.67) CNR2ALDH1A1HPGD
SCHEMBL29528611 0.76 CNR2 (0.74) CNR2ALDH1A1HPGD
SCHEMBL22722813 0.76 KDM4E (0.65) CNR2ALDH1A1HPGDSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 CNR2 663/4885ALDH1A1 964/4885HPGD 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.