SCHEMBL25516145

SCHEMBL25516145

OCc1ccc(C2(c3cccc(CO)c3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
OPRK1 P41145 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 1/20 0.39
ENPP2 Q13822 1/20 0.39
POLB P06746 1/20 0.37
MDM2 Q00987 1/20 0.34
CHEK1 O14757 1/20 0.34
RAF1 P04049 1/20 0.34
BRAF P15056 1/20 0.34
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1495219 0.94 PDK2 (0.47) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL14353392 0.88 MEN1 (0.57) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL31469068 0.83 PDK2 (0.48) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL18184923 0.82 MEN1 (0.50) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL25707003 0.79 PDK2 (0.48) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL17449849 0.77 KMT2A (0.45) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL13357078 0.77 PDK2 (0.42) PDK2MEN1KMT2AOPRK1KDM4E
SCHEMBL1495181 0.77 ESR1 (0.44) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL26719321 0.76 ESR1 (0.40) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL5846726 0.76 PDK2 (0.63) PDK2ESR1ESR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159752-A1 RESIN COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed