Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25533067 | 0.86 | BTK (0.44) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25523832 | 0.85 | MAPK13 (0.43) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25529347 | 0.85 | MAPK13 (0.43) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25516916 | 0.84 | MAPK13 (0.42) | KMT2AL3MBTL1BTKMAPK13 | |
| SCHEMBL25524768 | 0.84 | MAPK13 (0.44) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25417460 | 0.84 | MAPK13 (0.42) | KMT2AL3MBTL1BTKMAPK13 | |
| SCHEMBL25521406 | 0.84 | MAPK13 (0.42) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25523570 | 0.84 | BTK (0.44) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL25418148 | 0.84 | KIT (0.49) | KMT2AL3MBTL1BTKKITKDM1A | |
| SCHEMBL25521509 | 0.84 | KIT (0.49) | KMT2AL3MBTL1BTKKITKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |