SCHEMBL25517786

SCHEMBL25517786

CCCCC/C(=N\O)C(=O)c1ccc2c(c1)c1cc(C(=O)c3ccc(O)cc3)ccc1n2CC(CCCC)CCN1CCC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.40
CNR1 P21554 2/20 0.35
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
GFER P55789 1/20 0.34
NPY5R Q15761 2/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
UGCG Q16739 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25515581 0.88 CNR2 (0.42) CNR2CNR1KDM4ELMNAMAPT
SCHEMBL23801340 0.88 CNR2 (0.42) CNR2CNR1KDM4ELMNAMAPT
SCHEMBL25515585 0.88 CNR2 (0.42) CNR2CNR1KDM4ELMNAMAPT
SCHEMBL25515679 0.87 CNR2 (0.40) CNR2KDM4ELMNAMAPTHPGD
SCHEMBL25519569 0.84 CNR2 (0.38) CNR2CNR1LMNAMAPTNPY5R
SCHEMBL23801779 0.80 CNR2 (0.47) CNR2KDM4ELMNAMAPTHPGD
SCHEMBL25515451 0.80 CNR2 (0.47) CNR2KDM4ELMNAMAPTHPGD
SCHEMBL25517719 0.79 CNR2 (0.38) CNR2CNR1KDM4ELMNAMAPT
SCHEMBL23802438 0.79 CNR2 (0.46) CNR2KDM4ELMNAMAPTHPGD
SCHEMBL23801317 0.78 CNR2 (0.39) CNR2CNR1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 CNR2 663/4885CNR1 878/4885KDM4E 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.