Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24827973 | 1.00 | CYP2D6 (0.46) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL23594121 | 0.96 | CYP2D6 (0.49) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL24827986 | 0.88 | HRH3 (0.38) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL24827993 | 0.87 | CYP2D6 (0.44) | CYP2D6KCNH2HRH3 | |
| SCHEMBL24828018 | 0.85 | CYP2D6 (0.36) | CYP2D6KCNH2HRH3 | |
| SCHEMBL23594390 | 0.84 | CYP2D6 (0.40) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL24827855 | 0.81 | HRH3 (0.53) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL23298831 | 0.81 | HRH3 (0.53) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL25513416 | 0.79 | MEN1 (0.33) | CYP2D6KCNH2HRH3MEN1KMT2A | |
| SCHEMBL25850061 | 0.79 | CYP2D6 (0.37) | CYP2D6KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180427-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |