Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.49 |
| ▸ | KDM4A | O75164 | 13/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616306 | 0.80 | KDM4C (0.59) | KDM4CKDM4AEPHX2KDM5APHF8 | |
| SCHEMBL22856154 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL13951771 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL20158521 | 0.78 | EPHX2 (0.39) | KDM4CKDM4AEPHX2KDM5APHF8 | |
| SCHEMBL22522789 | 0.76 | KDM4C (0.41) | KDM4CKDM4AKDM5APHF8ALDH1A1 | |
| SCHEMBL23054880 | 0.76 | EPHX2 (0.62) | KDM4CKDM4AEPHX2KDM5APHF8 | |
| SCHEMBL26383116 | 0.75 | BLM (0.48) | KDM4CKDM4AKDM5AALDH1A1 | |
| SCHEMBL22790826 | 0.75 | MEN1 (0.35) | — | |
| SCHEMBL8339207 | 0.75 | MEN1 (0.35) | — | |
| SCHEMBL26280261 | 0.75 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078813-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |