Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 17/20 | 0.50 |
| ▸ | CDK2 | P24941 | 17/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 17/20 | 0.50 |
| ▸ | IGF1R | P08069 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959316 | 0.79 | CCNA2 (0.54) | CCNA2CDK2CCNA1IGF1R | |
| SCHEMBL7175766 | 0.73 | CCNA2 (0.51) | CCNA2CDK2CCNA1IGF1R | |
| SCHEMBL19954184 | 0.72 | CDK2 (0.41) | CCNA2CDK2CCNA1IGF1R | |
| SCHEMBL5868111 | 0.72 | CDK2 (0.69) | CCNA2CDK2CCNA1 | |
| SCHEMBL12413622 | 0.72 | HCAR2 (0.46) | CCNA2CDK2CCNA1 | |
| SCHEMBL18366169 | 0.71 | CCNA2 (0.50) | CCNA2CDK2CCNA1 | |
| SCHEMBL21779224 | 0.71 | DHODH (0.46) | CCNA2CDK2CCNA1 | |
| SCHEMBL22328204 | 0.69 | MAPK14 (0.41) | IGF1R | |
| SCHEMBL2321718 | 0.69 | IGF1R (0.68) | IGF1R | |
| SCHEMBL24759495 | 0.69 | HCAR2 (0.47) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | NANJING ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | RAD51, FANCI, BLM | CCNA2 2171/4885CDK2 2034/4885CCNA1 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.