Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 13/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522348 | 0.96 | FEN1 (0.36) | FEN1ALOX5APTLR9TLR8TLR7 | |
| SCHEMBL25520074 | 0.80 | RPS6KA3 (0.36) | FEN1ALOX5APVRK1 | |
| SCHEMBL25521661 | 0.78 | PDPK1 (0.41) | TLR9TLR8TLR7ABL1DYRK1A | |
| SCHEMBL25520068 | 0.77 | RPS6KA3 (0.45) | ESR1ESR2 | |
| SCHEMBL25522341 | 0.76 | RPS6KA3 (0.36) | FEN1ALOX5APTLR9TLR8TLR7 | |
| SCHEMBL25522438 | 0.76 | CYBB (0.34) | FEN1ALOX5APTLR9TLR8TLR7 | |
| SCHEMBL25520955 | 0.75 | EIF4A3 (0.36) | FEN1ALOX5APTLR9TLR8TLR7 | |
| SCHEMBL25522333 | 0.73 | RPS6KA3 (0.44) | ESR1ESR2 | |
| SCHEMBL25523362 | 0.72 | VRK1 (0.35) | VRK1 | |
| SCHEMBL25522346 | 0.72 | CYBB (0.34) | FEN1ALOX5APTLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |