Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24388852 | 0.89 | HTR2A (0.38) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL21921154 | 0.89 | PDPK1 (0.37) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL29603913 | 0.89 | PDPK1 (0.37) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL10159867 | 0.81 | MEN1 (0.37) | PDPK1HTR2ASLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL14449750 | 0.81 | MAPT (0.33) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL2581679 | 0.79 | PDPK1 (0.47) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL24388766 | 0.79 | PDPK1 (0.47) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL16448778 | 0.76 | SLC6A2 (0.43) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL17559137 | 0.75 | PDPK1 (0.40) | PDPK1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL2583993 | 0.73 | PDPK1 (0.53) | PDPK1HTR2AHRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183783-A1 | IMMUNOMODULATOR | Hitgen Inc. (CN) | 2023-05-24 | — | — | EP | disclosed |