SCHEMBL25523802

SCHEMBL25523802

Cc1cc(COCc2ccccc2)nc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
CYP1A2 P05177 1/20 0.50
BACE1 P56817 1/20 0.47
TSHR P16473 1/20 0.47
STAT3 P40763 1/20 0.47
HTT P42858 1/20 0.47
DHODH Q02127 1/20 0.44
PDE10A Q9Y233 3/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
CYSLTR1 Q9Y271 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967311 0.82 CYP1A2 (0.55) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL28589683 0.82 CYP1A2 (0.58) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL7967305 0.81 CYP1A2 (0.53) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL29082858 0.81 CYP1A2 (0.46) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL25523803 0.81 CYP1A2 (0.46) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL25523858 0.81 CYP1A2 (0.46) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL28585633 0.79 CYSLTR1 (0.57) KDM4EALDH1A1HPGDCYP1A2BACE1
SCHEMBL21848526 0.79 PDE10A (0.57) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL7968514 0.79 BACE1 (0.45) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL7968519 0.79 BACE1 (0.45) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023077218-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) 2023-05-11 WO disclosed