SCHEMBL25525232

SCHEMBL25525232

c1ccc2c(c1)c1cccc3c4cc5c(cc[n+]6ccccc56)nc4n2c13

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.37
MAPT P10636 6/20 0.37
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HPGD P15428 7/20 0.36
ALDH1A1 P00352 5/20 0.36
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 2/20 0.32
HTT P42858 1/20 0.32
CAMKK1 Q8N5S9 2/20 0.32
CAMKK2 Q96RR4 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CASP1 P29466 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25525261 0.84 KDM4E (0.39) KDM4EMAPTPOLBLMNATP53
SCHEMBL18502795 0.73 KDM4E (0.45) KDM4EMAPTPOLBLMNATP53
SCHEMBL18502793 0.67 KMT2A (0.53) KDM4EMAPTPOLBLMNATP53
SCHEMBL29600269 0.64 KDM4E (0.53) KDM4EMAPTPOLBHSD17B10HPGD
SCHEMBL25636917 0.64 KDM4E (0.53) KDM4EMAPTPOLBHSD17B10HPGD
SCHEMBL25635131 0.64 KDM4E (0.53) KDM4EMAPTPOLBHSD17B10HPGD
SCHEMBL867663 0.64 KDM4E (0.53) KDM4EMAPTPOLBHSD17B10HPGD
SCHEMBL17234519 0.64 KDM4E (0.42) KDM4EMAPTPOLBLMNATP53
SCHEMBL23995601 0.63 KDM4E (0.46) KDM4EMAPTPOLBHSD17B10HPGD
SCHEMBL19960360 0.63 KDM4E (0.44) KDM4EMAPTPOLBLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096072-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG Display Co.,Ltd. (KR) 2023-06-01 WO disclosed