SCHEMBL25525616

SCHEMBL25525616

CC(CN)CN1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ABCB1 P08183 1/20 0.43
ATM Q13315 1/20 0.41
PIK3CD O00329 1/20 0.40
HPGD P15428 1/20 0.39
EPHX2 P34913 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10320627 0.85 ABCB1 (0.51) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL10320433 0.85 ABCB1 (0.51) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL1554952 0.85 ABCB1 (0.51) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL23497107 0.84 USP2 (0.47) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL27036715 0.84 USP2 (0.47) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL24992871 0.84 USP2 (0.47) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL18852406 0.84 PIK3CD (0.58) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL20366188 0.84 ABCB1 (0.45) USP2SMN1; SMN2HTTALDH1A1CHRM2
Hydrochloric Acid SCHEMBL29935964 0.83 USP2 (0.46) USP2SMN1; SMN2HTTALDH1A1CHRM2
SCHEMBL16825817 0.83 USP2 (0.49) USP2SMN1; SMN2HTTALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078946-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed