Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 11/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.63 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.63 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.63 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.63 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR6 | P46095 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391731 | 0.91 | PRKAA2 (0.68) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2391773 | 0.90 | PRKAA2 (0.67) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2386404 | 0.88 | PRKAA2 (0.68) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2391795 | 0.87 | PRKAA2 (0.63) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2393716 | 0.85 | PRKAA2 (0.61) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2387758 | 0.85 | PRKAA2 (0.63) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2390761 | 0.82 | UTS2R (0.65) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL2389917 | 0.82 | MCHR1 (0.70) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL12227453 | 0.81 | POLB (0.61) | POLBCYP3A4MCHR1UTS2RMEN1 | |
| SCHEMBL2387674 | 0.81 | POLB (0.64) | POLBMCHR1UTS2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123681-A1 | METHODS FOR USING CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS | RIGEL PHARMACEUTICALS, INC. (US) | 2011-10-06 | — | — | WO | disclosed |