Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 17/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691378 | 0.99 | NR1I3 (0.62) | NR1I3DYRK1AUSP2ALDH1A1TSHR | |
| SCHEMBL22627537 | 0.84 | NR1I3 (0.62) | NR1I3USP2ALDH1A1TSHRHTT | |
| SCHEMBL1692245 | 0.84 | NR1I3 (0.55) | NR1I3DYRK1AGAAMAPT | |
| SCHEMBL1691688 | 0.84 | NR1I3 (0.57) | NR1I3DYRK1A | |
| SCHEMBL1691880 | 0.84 | NR1I3 (0.56) | NR1I3DYRK1AUSP2ALDH1A1TSHR | |
| SCHEMBL14646331 | 0.84 | DYRK1A (0.54) | NR1I3DYRK1A | |
| SCHEMBL22648873 | 0.84 | DYRK1A (0.56) | NR1I3DYRK1AUSP2ALDH1A1TSHR | |
| SCHEMBL22627421 | 0.81 | NR1I3 (0.69) | NR1I3 | |
| SCHEMBL1691260 | 0.80 | DYRK1A (0.56) | NR1I3DYRK1A | |
| SCHEMBL24517693 | 0.79 | NR1I3 (0.66) | NR1I3USP2ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376490-A1 | IMIDAZOPYRIDINE COMPOUNDS | Proximagen Limited (GB) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010064020-A1 | IMIDAZOPYRIDINE COMPOUNDS | PROXIMAGEN LTD. (GB) | 2010-06-10 | — | — | WO | disclosed |