Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.73 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25531606 | 0.93 | PIK3CA (0.67) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30336521 | 0.93 | PIK3CA (0.67) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25532395 | 0.93 | PIK3CA (0.67) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30335849 | 0.85 | PIK3CA (0.62) | PIK3CA | |
| SCHEMBL25532450 | 0.85 | PIK3CA (0.62) | PIK3CA | |
| SCHEMBL25532455 | 0.85 | PIK3CA (0.62) | PIK3CA | |
| SCHEMBL25181876 | 0.85 | PIK3CA (1.00) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30081699 | 0.85 | PIK3CA (1.00) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL23895729 | 0.85 | PIK3CA (1.00) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25531610 | 0.83 | PIK3CA (0.66) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081209-A1 | PI3K INHIBITORS AND METHODS OF TREATING CANCER | ZENO MANAGEMENT, INC. (US) | 2023-05-11 | — | — | WO | disclosed |