SCHEMBL255343

SCHEMBL255343

CC(=O)CC(=O)CC(C)(C)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
KDM6B O15054 1/20 0.42
KDM5C P41229 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
PHF8 Q9UPP1 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
PIK3CD O00329 1/20 0.40
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
HTT P42858 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TDP1 Q9NUW8 1/20 0.32
TRPA1 O75762 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914546 0.81 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL11789177 0.81 PIK3CD (0.41) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL3673428 0.80 HMGCR (0.45) KDM4EPIK3CDHMGCRCHRM1TBXA2R
SCHEMBL22660273 0.79 KDM4E (0.42) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL31555508 0.79 HMGCR (0.48) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL1536952 0.77 HMGCR (0.43) KDM4EPIK3CDHMGCRCHRM1TBXA2R
SCHEMBL28494 0.77
SCHEMBL4206545 0.76 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL8376125 0.75 KDM4E (0.35) KDM4EKDM6BKDM5CEGLN1PHF8
Acetone SCHEMBL2784800 0.75 HMGCR (0.41) PIK3CDHMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
WO-2012031025-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2012-03-08 WO disclosed
EP-0741120-B1 Polyalphaolefin dimers having low kinematic viscosities CHEVRON PHILLIPS CHEMICAL CO (US) 2003-03-26 EP disclosed
EP-0678493-B1 Controlled formation of olefin oligomers using boron trifluoride and a hydroxy carbonyl CHEVRON CHEM CO (US) 1998-12-30 EP disclosed
US-5817899-A BRANCHED OCTENE, DECENE AND TETRADECENE DIMERS CHEVRON CHEMICAL COMPANY (US) 1998-10-06 US disclosed
EP-0741120-A1 Polyalphaolefin dimers having low kinematic viscosities CHEVRON CHEMICAL COMPANY (US) 1996-11-06 EP disclosed
EP-0678493-A2 Controlled formation of olefin oligomers using boron trifluoride and a hydroxy carbonyl CHEVRON CHEMICAL COMPANY (US) 1995-10-25 EP disclosed
US-5420373-A USING BORON TRIFLUORIDE AND A HYDROXY CARBONYL PROMOTER CHEVRON CHEMICAL COMPANY (US) 1995-05-30 US disclosed