SCHEMBL25534818

SCHEMBL25534818

Cc1ccc(NC(=O)c2cc(N3CCOCC3)cc(C(F)(F)F)c2)cc1NC=O

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 6/20 0.71
MAPK14 Q16539 1/20 0.61
RAF1 P04049 14/20 0.57
BRAF P15056 14/20 0.57
LYN P07948 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19073521 0.92 CSF1R (0.59) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL25534482 0.90 CSF1R (0.70) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL4829508 0.85 CSF1R (0.68) CSF1RMAPK14RAF1BRAF
SCHEMBL25238622 0.83 CSF1R (1.00) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL6978589 0.83 CSF1R (0.72) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL19376879 0.82 CSF1R (0.85) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL5897191 0.82 CSF1R (0.74) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL19072897 0.81 CSF1R (0.57) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL4823998 0.79 BRAF (0.68) CSF1RMAPK14RAF1BRAFLYN
SCHEMBL1420016 0.79 RAF1 (0.65) CSF1RRAF1BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096304-A1 ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF 한양대학교 에리카산학협력단 2023-06-01 WO disclosed