Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367229 | 0.84 | — | — | |
| SCHEMBL18241852 | 0.79 | — | — | |
| SCHEMBL8860005 | 0.77 | — | — | |
| SCHEMBL29155968 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL28931198 | 0.75 | — | — | |
| SCHEMBL18242263 | 0.75 | — | — | |
| SCHEMBL13763530 | 0.74 | — | — | |
| SCHEMBL9750949 | 0.72 | TSHR (0.46) | TSHR | |
| SCHEMBL988101 | 0.72 | — | — | |
| SCHEMBL5918539 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030683-A2 | NOVEL SINGLE CHEMICAL ENTITIES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2012-03-08 | — | — | WO | disclosed |