Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 17/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 17/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 17/20 | 0.42 |
| ▸ | BIRC8 | Q96P09 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973505 | 0.87 | XIAP (0.48) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL9975084 | 0.87 | XIAP (0.48) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL22479086 | 0.82 | XIAP (0.41) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL23833068 | 0.82 | XIAP (0.41) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL27270277 | 0.81 | XIAP (0.37) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL9973500 | 0.81 | XIAP (0.47) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL9973548 | 0.81 | XIAP (0.47) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL14528269 | 0.81 | FDFT1 (0.52) | FDFT1XIAP | |
| SCHEMBL2031723 | 0.81 | FDFT1 (0.52) | FDFT1XIAP | |
| SCHEMBL14528265 | 0.81 | FDFT1 (0.52) | FDFT1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159573-A1 | SMALL MOLECULE STAT PROTEIN DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159573-A1 | SMALL MOLECULE STAT PROTEIN DEGRADERS | STAT1, STAT3, STAT5A | FDFT1 3797/4885XIAP 1959/4885BIRC3 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.