Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25207474 | 0.99 | PDE4B (0.52) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL25228900 | 0.95 | NAMPT (0.51) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL15157112 | 0.87 | NAMPT (0.54) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL30778326 | 0.87 | NAMPT (0.54) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL5805967 | 0.86 | NAMPT (0.51) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL24793972 | 0.84 | NAMPT (0.52) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL12479918 | 0.84 | NAMPT (0.52) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL25227116 | 0.84 | PDE4B (0.51) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL15862956 | 0.83 | NAMPT (0.51) | PDE4BNAMPTKDM4EMAPTTHRB | |
| SCHEMBL29976347 | 0.83 | KDM4E (0.53) | PDE4BNAMPTKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096304-A1 | ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-06-01 | — | — | WO | disclosed |