Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.33 |
| ▸ | AURKA | O14965 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25540960 | 0.86 | BTK (0.40) | BTKKMT2AL3MBTL1MAPK13HDAC3 | |
| SCHEMBL25525729 | 0.84 | BTK (0.43) | BTKKMT2AL3MBTL1MAPK13CA1 | |
| SCHEMBL25523570 | 0.83 | BTK (0.44) | BTKKMT2AL3MBTL1MAPK13MAP4K4 | |
| SCHEMBL25525053 | 0.83 | BTK (0.40) | BTKKMT2AL3MBTL1CDK9KAT8 | |
| SCHEMBL25529347 | 0.82 | MAPK13 (0.43) | BTKKMT2AL3MBTL1MAPK13MAP4K4 | |
| SCHEMBL25523832 | 0.82 | MAPK13 (0.43) | BTKKMT2AL3MBTL1MAPK13MAP4K4 | |
| SCHEMBL25525026 | 0.82 | BTK (0.40) | BTKKMT2AL3MBTL1MAPK13 | |
| SCHEMBL25525052 | 0.81 | BTK (0.43) | BTKKMT2AL3MBTL1MAPK13CDK9 | |
| SCHEMBL25533067 | 0.81 | BTK (0.44) | BTKKMT2AL3MBTL1MAPK13MAP4K4 | |
| SCHEMBL30397566 | 0.81 | BTK (0.40) | BTKKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |