Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.56 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25542301 | 0.92 | EZH2 (0.48) | EZH2EZH1HDAC6 | |
| SCHEMBL19391370 | 0.92 | EZH2 (0.66) | EZH2EZH1 | |
| SCHEMBL19391565 | 0.90 | EZH2 (0.48) | EZH2EZH1 | |
| SCHEMBL19391569 | 0.87 | EZH2 (0.56) | EZH2 | |
| SCHEMBL19391617 | 0.87 | EZH2 (0.55) | EZH2 | |
| SCHEMBL19391702 | 0.87 | EZH2 (0.55) | EZH2 | |
| SCHEMBL19391307 | 0.87 | EZH2 (0.60) | EZH2EZH1 | |
| SCHEMBL19391614 | 0.85 | EZH2 (0.57) | EZH2EZH1 | |
| SCHEMBL19391408 | 0.85 | EZH2 (0.59) | EZH2EZH1 | |
| SCHEMBL25542122 | 0.85 | EZH2 (0.44) | EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |