Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 13/20 | 0.54 |
| ▸ | EZH1 | Q92800 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | EED | O75530 | 3/20 | 0.47 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.47 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.47 |
| ▸ | RBBP7 | Q16576 | 3/20 | 0.47 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684492 | 0.84 | EZH2 (0.60) | EZH2EZH1HDAC6EEDRBBP4 | |
| SCHEMBL12684439 | 0.78 | EZH2 (0.60) | EZH2EZH1HDAC6EEDRBBP4 | |
| SCHEMBL12498441 | 0.74 | EZH2 (0.65) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL12684460 | 0.73 | EZH2 (0.62) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL2595453 | 0.73 | EZH2 (0.71) | EZH2EZH1HDAC6HDAC1EED | |
| SCHEMBL12684211 | 0.72 | EZH2 (0.67) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL21418342 | 0.72 | EZH2 (0.48) | EZH2EZH1HDAC6HDAC1EED | |
| SCHEMBL19391463 | 0.71 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL15491016 | 0.70 | EZH2 (0.67) | EZH2EZH1HDAC6EEDRBBP4 | |
| SCHEMBL19391672 | 0.69 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |