Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.57 |
| ▸ | EED | O75530 | 7/20 | 0.46 |
| ▸ | RBBP4 | Q09028 | 7/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 7/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 5/20 | 0.46 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.45 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25544335 | 0.84 | EZH2 (0.62) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20170148 | 0.84 | EZH2 (0.51) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684458 | 0.83 | EZH2 (0.76) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL25548373 | 0.83 | EZH2 (0.51) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19391592 | 0.81 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12EZH1 | |
| SCHEMBL19391525 | 0.81 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19621015 | 0.80 | EZH2 (0.43) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19657083 | 0.80 | EZH2 (0.59) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL25544745 | 0.78 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19620738 | 0.77 | EZH2 (0.54) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-B1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | EPIZYME INC (US) | 2023-05-10 | — | — | EP | disclosed |