SCHEMBL25545272

SCHEMBL25545272

COC[C@@H]1[C@@H](C)[C@@H](C)CN1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.32
MGAM O43451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22220484 0.77 GAA (0.48) GAAMGAM
SCHEMBL12453749 0.75 GAA (0.31) GAAMGAM
SCHEMBL14438560 0.75 GAA (0.31) GAAMGAM
SCHEMBL24176141 0.72
SCHEMBL24785031 0.70 GBA1 (0.33)
SCHEMBL24784979 0.68 GAA (0.31) GAAMGAM
SCHEMBL24785773 0.68 GAA (0.31) GAAMGAM
SCHEMBL24996828 0.67 GAA (0.31) GAAMGAM
SCHEMBL12149606 0.67 GAA (0.68) GAAMGAM
SCHEMBL24996753 0.67 GAA (0.31) GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023086383-A1 SELECT KRAS G12C INHIBITORS AND USES THEREOF 1200 PHARMA LLC (US) 2023-05-19 WO disclosed