SCHEMBL25547

SCHEMBL25547

Cn1cnc2nc(N)[nH]c(=O)c21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.49
CYP3A4 P08684 2/20 0.47
PMP22 Q01453 2/20 0.47
MAPK1 P28482 1/20 0.47
PNP P00491 2/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
THRB P10828 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDE4A P27815 1/20 0.42
ADORA2A P29274 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
CYP1A2 P05177 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28768404 0.92 EIF4E (0.46) GDACYP3A4PMP22MAPK1PNP
Phosphoric Acid SCHEMBL20856962 0.91 EIF4E (0.46) GDACYP3A4PMP22MAPK1PNP
Pyridine SCHEMBL28098163 0.90 GDA (0.41) GDACYP3A4PMP22MAPK1PNP
SCHEMBL23365318 0.89 ADORA2A (0.43) GDACYP3A4PMP22MAPK1PNP
SCHEMBL6528880 0.87 HSD17B10 (0.41) GDACYP3A4PMP22MAPK1PNP
Guanine SCHEMBL21840391 0.87 PNP (0.68) GDACYP3A4PMP22MAPK1PNP
SCHEMBL19461404 0.86 PNP (0.47) PNPALDH1A1MAPTTHRBKDM4E
Guanine SCHEMBL21840390 0.85 PNP (0.43) GDACYP3A4PMP22MAPK1PNP
Triphosphate SCHEMBL28768402 0.85 POLB (0.51) CYP3A4PMP22MAPK1PNPEIF4E
Beta-Alanine SCHEMBL23300588 0.85 AKR1B1 (0.41) GDACYP3A4PMP22MAPK1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 45415 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
WO-2026107204-A1 METHODS FOR ANALYZING LOW-DEPTH GENOME SEQUENCING DATA TO DETECT MINIMAL RESIDUAL DISEASE GUARDANT HEALTH, INC. (US) 2026-05-21 WO claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-20260125686-A1 COMPOSITIONS AND METHODS FOR MODULATION OF CFTR CYSTIC FIBROSIS FOUND (US) 2026-05-07 US claimed
EP-4735040-A1 OPHTHALMIC VISCOELASTIC DEVICE AND KIT FOR USE IN EYE SURGERY Carl Zeiss Meditec AG (DE) 2026-05-06 EP claimed
WO-2026090123-A1 METHODS AND COMPOSITIONS FOR MANAGING PESTS UOVO INTERNATIONAL LLC (US) 2026-04-30 WO claimed
WO-2026088246-A1 METHOD FOR PRODUCING LOW-MOLECULAR-WEIGHT COMPOUND NTT株式会社 2026-04-30 WO claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 WO claimed
EP-1117838-A1 A METHOD FOR ANALYZING POLYNUCLEOTIDES Variagenics, Inc. (US) 2001-07-25 EP claimed
CN-1261373-A Compositions and methods for activating genes of interest CHARLES ALLEN BLACK JR (US) 2000-07-26 CN claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
EP-0993468-A1 COMPOSITIONS AND METHODS FOR ACTIVATING GENES OF INTEREST Black, Charles Allen Jr. (US) 2000-04-19 EP claimed
WO-2000018967-A1 A METHOD FOR ANALYZING POLYNUCLEOTIDES VARIAGENICS, INC. (US) 2000-04-06 WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
EP-0540693-B1 THE REDUCTION OF NON-SPECIFIC AMPLIFICATION DURING $i(IN VITRO) NUCLEIC ACID AMPLIFICATION USING MODIFIED NUCLEIC ACID BASES HOFFMANN LA ROCHE (CH) 1999-01-20 EP claimed
WO-1998058944-A1 COMPOSITIONS AND METHODS FOR ACTIVATING GENES OF INTEREST BLACK CHARLES ALLEN JR (US) 1998-12-30 WO claimed