Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CCR1 | P32246 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | CCR8 | P51685 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425309 | 0.93 | KDM4E (0.69) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL2197485 | 0.87 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL29244073 | 0.85 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL2202802 | 0.84 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL29398228 | 0.84 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL29756481 | 0.84 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL367895 | 0.84 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL2365362 | 0.83 | KDM4E (0.44) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL2199703 | 0.83 | KDM4E (0.55) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL2198833 | 0.81 | SMN1; SMN2 (0.53) | KDM4ESMN1; SMN2TP53LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556075-A1 | SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011125020-A1 | SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2011-10-13 | — | — | WO | disclosed |