Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.53 |
| ▸ | PYGL | P06737 | 15/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460867 | 0.93 | CXCR2 (0.62) | CXCR2PYGLCYP2C9MRGPRX4 | |
| SCHEMBL25548930 | 0.93 | CXCR2 (0.62) | CXCR2PYGLCYP2C9MRGPRX4 | |
| SCHEMBL23461213 | 0.93 | CXCR2 (0.62) | CXCR2PYGLCYP2C9MRGPRX4 | |
| SCHEMBL23460868 | 0.93 | CXCR2 (0.62) | CXCR2PYGLCYP2C9MRGPRX4 | |
| SCHEMBL25549096 | 0.88 | CXCR2 (0.49) | CXCR2PYGLCYP2C9 | |
| SCHEMBL25552982 | 0.87 | CXCR2 (0.48) | CXCR2PYGLCYP2C9 | |
| SCHEMBL25548931 | 0.87 | CXCR2 (0.48) | CXCR2PYGLCYP2C9 | |
| SCHEMBL23461910 | 0.86 | CXCR2 (0.52) | CXCR2MRGPRX4 | |
| SCHEMBL38664653 | 0.86 | CXCR2 (0.52) | CXCR2MRGPRX4 | |
| SCHEMBL23461911 | 0.86 | CXCR2 (0.52) | CXCR2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | CXCR2 1205/4885PYGL 1117/4885CYP2C9 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.