Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151568 | 0.84 | MCHR1 (0.53) | MCHR1KCNH2HRH3PPARD | |
| SCHEMBL12289356 | 0.81 | MCHR1 (0.53) | MCHR1KCNH2HRH3 | |
| SCHEMBL2565391 | 0.81 | MCHR1 (0.55) | MCHR1KCNH2HRH3 | |
| SCHEMBL14150356 | 0.78 | MCHR1 (0.56) | MCHR1KCNH2HRH3PPARGPPARD | |
| SCHEMBL14151155 | 0.77 | MCHR1 (0.53) | MCHR1KCNH2HRH3 | |
| SCHEMBL2567537 | 0.77 | MCHR1 (0.52) | MCHR1KCNH2HRH3 | |
| SCHEMBL14151083 | 0.77 | MCHR1 (0.56) | MCHR1KCNH2HRH3 | |
| SCHEMBL14150435 | 0.76 | MCHR1 (0.52) | MCHR1KCNH2HRH3 | |
| SCHEMBL2571449 | 0.76 | MCHR1 (0.66) | MCHR1KCNH2HRH3 | |
| SCHEMBL1005304 | 0.76 | MCHR1 (0.60) | MCHR1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011127643-A1 | PYRIDONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-10-20 | — | — | WO | disclosed |