Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460977 | 0.91 | CXCR2 (0.50) | CXCR2LRRK2ADAMTS4MMP13KIFC1 | |
| SCHEMBL23460975 | 0.91 | CXCR2 (0.50) | CXCR2LRRK2ADAMTS4MMP13KIFC1 | |
| SCHEMBL38662651 | 0.91 | CXCR2 (0.50) | CXCR2LRRK2ADAMTS4MMP13KIFC1 | |
| SCHEMBL25548983 | 0.90 | PTGDR2 (0.37) | CXCR2TRPV1MRGPRX4MMP2MMP9 | |
| SCHEMBL25549139 | 0.90 | CXCR2 (0.40) | CXCR2KIFC1PTPN1PTPN2 | |
| SCHEMBL25548976 | 0.89 | CXCR2 (0.36) | CXCR2ADAMTS4MMEACECPA1 | |
| SCHEMBL25548984 | 0.89 | CXCR2 (0.59) | CXCR2ADAMTS4MMP13KIFC1MME | |
| SCHEMBL23460751 | 0.84 | CXCR2 (0.51) | CXCR2LRRK2ADAMTS4MMP13KIFC1 | |
| SCHEMBL23460749 | 0.84 | CXCR2 (0.51) | CXCR2LRRK2ADAMTS4MMP13KIFC1 | |
| SCHEMBL38147176 | 0.84 | CXCR2 (0.51) | CXCR2LRRK2ADAMTS4MMP13KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | CXCR2 1205/4885LRRK2 3499/4885ADAMTS4 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.