SCHEMBL25549210

SCHEMBL25549210

Clc1ccc2c(ccc3nc(-c4ccccc4)oc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.57
CASP3 P42574 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
ELANE P08246 1/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
DHODH Q02127 1/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
TP53 P04637 3/20 0.43
TSHR P16473 2/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
PTPN2 P17706 2/20 0.43
PTPN1 P18031 2/20 0.43
PTPN5 P54829 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25550019 0.97 SMN1; SMN2 (0.55) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL18544701 0.90 SMN1; SMN2 (0.54) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL31364269 0.90 SMN1; SMN2 (0.54) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL19452495 0.90 SMN1; SMN2 (0.59) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL27383240 0.89 SMN1; SMN2 (0.52) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL25551226 0.87 CYP2A6 (0.46) SMN1; SMN2CASP3SENP7SENP6ESR1
SCHEMBL25550142 0.87 SMN1; SMN2 (0.56) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL25898079 0.83 CYP1A1 (0.50) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL30201111 0.83 SMN1; SMN2 (0.55) SMN1; SMN2CASP3SENP7SENP6ELANE
SCHEMBL18814306 0.83 SMN1; SMN2 (0.55) SMN1; SMN2CASP3SENP7SENP6ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4276924-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-15 EP disclosed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed
WO-2023085908-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed