SCHEMBL25549850

SCHEMBL25549850

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)NCCCC[C@H](NC(=O)CCCCCCC/C=C\C/C=C\C/C=C\CC)C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 7/20 0.53
▸ EPHX2 P34913 4/20 0.52
▸ KDM4E B2RXH2 1/20 0.51
▸ ALDH1A1 P00352 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ TRPV1 Q8NER1 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ ALOX12 P18054 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ FAAH O00519 2/20 0.49
▸ CNR2 P34972 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15124523 0.95 CNR1 (0.57) CNR1EPHX2ALDH1A1TRPV1MEN1
SCHEMBL15124524 0.95 CNR1 (0.57) CNR1EPHX2ALDH1A1TRPV1MEN1
SCHEMBL15124522 0.95 CNR1 (0.57) CNR1EPHX2ALDH1A1TRPV1MEN1
SCHEMBL15124015 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT
SCHEMBL15124016 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT
SCHEMBL15124286 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT
SCHEMBL15124283 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT
SCHEMBL25549752 0.93 CNR1 (0.63) CNR1EPHX2KDM4EALDH1A1HPGD
SCHEMBL15124014 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT
SCHEMBL15124284 0.93 CNR1 (0.55) CNR1EPHX2ALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NOVARTIS AG (CH) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NSUN2, NSUN3, POLM CNR1 4709/4885EPHX2 3717/4885KDM4E 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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