Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.57 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554425 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL2554868 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL16649791 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL15136180 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL2555606 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL414576 | 1.00 | HMGCR (0.62) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL2201502 | 0.91 | HMGCR (0.72) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL2181335 | 0.91 | HMGCR (0.72) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL4231623 | 0.91 | HMGCR (0.72) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL2180780 | 0.91 | HMGCR (0.72) | HMGCRPTPN7SELPMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2553528-B1 | PLASTICS COLOURATION | DATALASE LTD (GB) | 2015-04-22 | — | — | EP | claimed |
| US-20130196176-A1 | Plastics Colouration | DATALASE LTD. (UK) | 2013-08-01 | — | — | US | claimed |
| EP-2553528-A1 | PLASTICS COLOURATION | Datalase Limited (GB) | 2013-02-06 | — | — | EP | claimed |
| WO-2011121265-A1 | PLASTICS COLOURATION | DATALASE LTD. (GB) | 2011-10-06 | — | — | WO | claimed |