Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | UGCG | Q16739 | 3/20 | 0.33 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25548999 | 1.00 | EGLN1 (0.42) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL25601641 | 0.87 | CXCR2 (0.44) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL23460143 | 0.87 | CXCR2 (0.44) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL23460144 | 0.87 | CXCR2 (0.44) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL25549159 | 0.86 | EGLN1 (0.42) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL25556126 | 0.86 | EGLN1 (0.42) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL23459945 | 0.86 | EGLN1 (0.43) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL23459947 | 0.86 | EGLN1 (0.43) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL25599253 | 0.86 | EGLN1 (0.43) | EGLN1CXCR2MAPTALDH1A1KDM4E | |
| SCHEMBL25549184 | 0.85 | CXCR2 (0.44) | EGLN1CXCR2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | EGLN1 623/4885CXCR2 1205/4885MAPT 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.