SCHEMBL25554227

SCHEMBL25554227

Clc1ccc2c(ccc3oc(-c4ccc(-c5ccccc5)cc4)nc32)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.58
CASP3 P42574 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
RCE1 Q9Y256 1/20 0.47
KDM4E B2RXH2 5/20 0.46
HPGD P15428 4/20 0.46
ALDH1A1 P00352 3/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
LMNA P02545 1/20 0.46
ADK P55263 1/20 0.44
PTPN1 P18031 8/20 0.44
PTPN2 P17706 2/20 0.44
PTPN5 P54829 1/20 0.44
RAB9A P51151 6/20 0.43
NPC1 O15118 4/20 0.43
HTT P42858 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25551820 0.97 SMN1; SMN2 (0.61) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL25898358 0.90 SMN1; SMN2 (0.60) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL25555738 0.88 MAPT (0.47) SMN1; SMN2CASP3SENP7SENP6KDM4E
SCHEMBL27383292 0.88 SMN1; SMN2 (0.57) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL25551888 0.87 SMN1; SMN2 (0.63) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL17281512 0.83 RCE1 (0.54) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL21000664 0.83 RCE1 (0.47) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL21000749 0.83 RCE1 (0.47) SMN1; SMN2CASP3SENP7SENP6RCE1
SCHEMBL2245016 0.82 PTPN1 (0.56) SMN1; SMN2CASP3SENP7SENP6KDM4E
SCHEMBL19452267 0.82 RCE1 (0.48) SMN1; SMN2CASP3SENP7SENP6RCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4276924-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-15 EP disclosed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed
WO-2023085908-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed