Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 6/20 | 0.63 |
| ▸ | RORC | P51449 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330083 | 0.92 | HRH3 (0.68) | HRH3BCHERORCCNR2OPRM1 | |
| Hydrochloric Acid SCHEMBL17710415 | 0.90 | HRH3 (0.65) | HRH3BCHERORCCNR2OPRM1 | |
| Water SCHEMBL28117059 | 0.90 | HRH3 (0.65) | HRH3BCHERORCCNR2OPRM1 | |
| SCHEMBL8240347 | 0.87 | HRH3 (0.61) | HRH3BCHERORCCNR2OPRM1 | |
| Hydrochloric Acid SCHEMBL3183297 | 0.85 | HRH3 (0.59) | HRH3BCHERORCCNR2OPRM1 | |
| SCHEMBL11197923 | 0.84 | HRH3 (0.59) | HRH3BCHERORCCNR2OPRM1 | |
| SCHEMBL9485158 | 0.84 | MAPT (0.61) | HRH3BCHERORCOPRM1DRD3 | |
| SCHEMBL29336127 | 0.84 | BCHE (0.67) | BCHEKCNH2TSHR | |
| SCHEMBL20145799 | 0.83 | HRH3 (0.57) | HRH3BCHERORCCNR2OPRM1 | |
| SCHEMBL9286253 | 0.83 | HRH3 (0.57) | HRH3BCHERORCCNR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081370-A1 | TREATMENT WITH ILEAL BILE ACID TRANSPORTER (IBAT) INHIBITORS FOR INCREASED EVENT-FREE SURVIVAL (EFS) | MIRUM PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |