Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 7/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 5/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549146 | 1.00 | CXCR2 (0.40) | CXCR2CNR2CNR1KCNK2ABHD12 | |
| SCHEMBL23461057 | 0.90 | CXCR2 (0.44) | CXCR2CNR2CNR1KCNK2 | |
| SCHEMBL23461056 | 0.90 | CXCR2 (0.44) | CXCR2CNR2CNR1KCNK2 | |
| SCHEMBL25555858 | 0.90 | CXCR2 (0.37) | CXCR2CNR2CNR1KCNK2PDE2A | |
| SCHEMBL23461459 | 0.88 | CNR2 (0.35) | CXCR2CNR2CNR1ABHD12ABHD6 | |
| SCHEMBL23461458 | 0.88 | CNR2 (0.35) | CXCR2CNR2CNR1ABHD12ABHD6 | |
| SCHEMBL38666109 | 0.88 | CXCR2 (0.43) | CXCR2KCNK2PDE2A | |
| SCHEMBL23460924 | 0.88 | CXCR2 (0.43) | CXCR2KCNK2PDE2A | |
| SCHEMBL23460926 | 0.88 | CXCR2 (0.43) | CXCR2KCNK2PDE2A | |
| SCHEMBL23461078 | 0.87 | CXCR2 (0.37) | CXCR2CNR2CNR1KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159438-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | CXCR2 1205/4885CNR2 716/4885CNR1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.