SCHEMBL25556872

CNC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1

nearest known ligand 0.76

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	SSTR2	P30874	15/20	0.76

▸	SSTR5	P35346	12/20	0.76

▸	SSTR4	P31391	11/20	0.76

▸	SSTR3	P32745	6/20	0.76

▸	SSTR1	P30872	3/20	0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25556866	0.97	SSTR2 (0.77)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL20725177	0.94	SSTR2 (0.84)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL20725182	0.94	SSTR2 (0.84)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL24160859	0.94	SSTR2 (0.83)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL21096706	0.94	SSTR2 (0.78)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL20725189	0.92	SSTR2 (0.73)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL20725184	0.92	SSTR2 (0.73)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL23482744	0.91	SSTR2 (0.88)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL29414545	0.90	SSTR2 (0.84)	SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL20725181	0.89	SSTR2 (0.83)	SSTR2SSTR5SSTR4SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023098831-A1	TARGETED PROTEASE DEGRADATION (TED) PLATFORM	嘉兴优博生物技术有限公司	2023-06-08	—	—	WO	disclosed