Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555735 | 1.00 | EIF2AK2 (0.42) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL18503835 | 0.81 | MAPT (0.45) | MIFKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1403486 | 0.77 | MAPT (0.46) | MAPTWDR5 | |
| SCHEMBL4714050 | 0.77 | ESR1 (0.50) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL4714044 | 0.77 | ESR1 (0.50) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL1793926 | 0.76 | ERN1 (0.46) | CA1CA2ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL5448079 | 0.76 | EIF2AK2 (0.55) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL5906775 | 0.74 | EIF2AK2 (0.49) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL16634243 | 0.73 | BACE1 (0.47) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF | |
| SCHEMBL1469976 | 0.73 | MIF (0.67) | EIF2AK2CSNK2A2CSNK2BCSNK2A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |