⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20017949 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3546439 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL27663485 | 0.97 | — | — | |
| Methylene Chloride SCHEMBL28239825 | 0.92 | TSHR (0.32) | — | |
| Alcohol SCHEMBL28679278 | 0.89 | TSHR (0.31) | — | |
| 1,2-Dichloroethane SCHEMBL28112515 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL3650782 | 0.85 | TSHR (0.39) | — | |
| SCHEMBL609519 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL22299925 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL1126983 | 0.78 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11274 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746863-A1 | ENDOXIFEN COMPOSITIONS AND METHODS OF USE THEREOF AND SYNTHESIS THEREOF | Atossa Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4747229-A1 | ANTI-TUMOR COMPOUNDS AND METHODS OF USE THEREOF AND SYNTHESIS THEREOF | Atossa Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| US-20260028308-A1 | METHODS FOR MAKING AND USING ENDOXIFEN | ATOSSA THERAPEUTICS INC (US) | 2026-01-29 | — | — | US | claimed |
| EP-4635941-A1 | PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE | Nouryon Chemicals International B.V. (NL) | 2025-10-22 | — | — | EP | claimed |
| EP-4471010-B1 | PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE | NOURYON CHEMICALS INT BV (NL) | 2025-06-04 | — | — | EP | claimed |
| CN-116496445-B | Star polymer, preparation method and application thereof, dispersing agent and dispersing method | 中国科学院宁波材料技术与工程研究所 | 2025-05-30 | — | — | CN | claimed |
| CN-120025337-A | Preparation method of baroretinib | 合肥菁科生物科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| US-12291505-B2 | Methods for the synthesis of deuterated dextromethorphan | AVANIR PHARMACEUTICALS, INC. (US) | 2025-05-06 | — | — | US | claimed |
| CN-117865889-B | Benzisoquinolines method for synthesizing compound | 山东省药学科学院 | 2025-04-29 | — | — | CN | claimed |
| US-20250109415-A1 | SUSTAINABLE FUNCTIONALIZATION AND METHODS OF USE THEREOF | UNIV ARIZONA STATE (US) | 2025-04-03 | — | — | US | claimed |
| US-5187306-A | Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters | NIPPON PAINT CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| EP-0385237-A2 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | claimed |
| EP-0333026-A1 | 3-(2,3,4,5,6-Pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-20 | — | — | EP | claimed |
| EP-0328830-A1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-08-23 | — | — | EP | claimed |
| EP-0271798-A2 | O-Substituted tetrahydropyridine oxime cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-06-22 | — | — | EP | claimed |
| EP-0265734-A1 | Piperidin-4-yl-tetracyclic benzodiazepines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-05-04 | — | — | EP | claimed |
| EP-0223403-A2 | Piperidine derivative, its preparation, and its use as medicament | BEECHAM GROUP PLC (GB) | 1987-05-27 | — | — | EP | claimed |
| EP-0040153-B1 | PROCESS FOR THE SYNTHESIS OF ALPHA-CHLORINATED CHLOROFORMIATES, AND NOVEL ALPHA-CHLORINATED CHLOROFORMIATES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1985-07-31 | — | — | EP | claimed |
| EP-0045234-B1 | DEALKYLATION PROCESS FOR TERTIARY AMINES BY THE USE OF ALPHA-CHLORINATED CHLOROFORMIATES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1984-05-23 | — | — | EP | claimed |
| US-4125601-A | Substituted nitroaminophenols, process for their preparation and dyeing compositions in which they are present | L'OREAL (FR) | 1978-11-14 | — | — | US | claimed |