Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165010 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29635692 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL162602 | 0.84 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL164505 | 0.82 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635831 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL161598 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL165297 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL174294 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL164817 | 0.80 | NAMPT (0.84) | NAMPTCYP2C9 | |
| SCHEMBL163838 | 0.79 | NAMPT (1.00) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031196-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL] AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |