Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25587863 | 0.83 | POLG (0.39) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL23171238 | 0.83 | POLG (0.40) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL25564081 | 0.83 | P2RY2 (0.41) | P2RY2P2RY4P2RY6 | |
| SCHEMBL23225632 | 0.82 | POLG (0.40) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL19993771 | 0.82 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL25586978 | 0.81 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL20611059 | 0.81 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL25587616 | 0.80 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL19866483 | 0.80 | POLG (0.43) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL23170977 | 0.77 | POLG (0.43) | POLGP2RY2P2RY4P2RY6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |