Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 19/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 19/20 | 0.46 |
| ▸ | KAT6B | Q8WYB5 | 15/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 13/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 13/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30020281 | 0.81 | KAT7 (0.70) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25561771 | 0.81 | KAT7 (0.70) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL22817330 | 0.79 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL22817393 | 0.78 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30019841 | 0.77 | PDE4B (0.45) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25564685 | 0.77 | PDE4B (0.45) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25563986 | 0.76 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL22817394 | 0.75 | KAT7 (0.67) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25563914 | 0.74 | KAT7 (0.57) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25564128 | 0.74 | KAT7 (0.58) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |