Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166348 | 0.87 | KMT2A (0.45) | PARP10MEN1KMT2AADRA2AMAPT | |
| SCHEMBL28045267 | 0.81 | KDM4E (0.57) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL27249089 | 0.81 | PARP10 (0.56) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL29047414 | 0.81 | KDM4E (0.50) | PARP10KDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL16962824 | 0.81 | KDM4E (0.47) | PARP10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1785633 | 0.80 | PARP10 (0.54) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL6838380 | 0.79 | KDM4E (0.68) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL5952448 | 0.78 | PARP10 (0.56) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL10407907 | 0.78 | PLAU (0.58) | PARP10KDM4EALDH1A1MEN1PKM | |
| SCHEMBL16956617 | 0.77 | KDM4E (0.44) | PARP10KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028676-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |