SCHEMBL25565376

SCHEMBL25565376

Cc1ccc(-c2ccc(OCC3CCC(C4CCC(C)CC4)CC3)c(F)c2F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.35
HPGD P15428 3/20 0.35
SCN9A Q15858 4/20 0.34
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
RIPK1 Q13546 1/20 0.33
FFAR1 O14842 2/20 0.32
PPARD Q03181 1/20 0.32
BRD4 O60885 4/20 0.32
KCNN4 O15554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18773601 0.95 HPGD (0.37) PDE10AHPGDSCN9AHTR2AHTR2C
SCHEMBL10454692 0.95 HPGD (0.37) PDE10AHPGDSCN9AHTR2AHTR2C
SCHEMBL10454746 0.91 HPGD (0.39) PDE10AHPGDSCN9AHTR2AHTR2C
SCHEMBL31338 0.91 HPGD (0.39) PDE10AHPGDSCN9AHTR2AHTR2C
SCHEMBL26277379 0.89 HTR2A (0.39) PDE10AHTR2AHTR2CHTR2BNOS3
SCHEMBL24170506 0.88 HPGD (0.40) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL12205251 0.88 HPGD (0.40) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL16769005 0.85 HTR2A (0.36) PDE10AHPGDHTR2AHTR2CHTR2B
SCHEMBL16769006 0.85 HTR2A (0.36) PDE10AHPGDHTR2AHTR2CHTR2B
SCHEMBL26277386 0.85 HTR2A (0.36) PDE10AHTR2AHTR2CHTR2BNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-20240026223-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-01-25 US disclosed
US-11827829-B2 Liquid crystal composition containing dibenzo derivative and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-11-28 US disclosed
US-11788010-B2 Liquid crystal composition and liquid crystal display device comprising the same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-17 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20230257654-A1 LIQUID CRYSTAL COMPOSITION CONTAINING DIBENZO DERIVATIVES AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-08-17 US disclosed
US-20230159826-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-25 US disclosed