SCHEMBL25567159

SCHEMBL25567159

CC(C)(C)c1cnc(NC2CCC(=O)NC2=O)cn1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.71
CRBN Q96SW2 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21965809 0.83 DDB1 (1.00) DDB1CRBN
SCHEMBL23593988 0.82 DDB1 (0.59) DDB1CRBN
SCHEMBL23594346 0.80 DDB1 (0.61) DDB1CRBN
SCHEMBL24481172 0.79 DDB1 (0.58) DDB1CRBN
SCHEMBL25091488 0.78 DDB1 (0.71) DDB1CRBN
SCHEMBL24480350 0.78 DDB1 (0.70) DDB1CRBN
SCHEMBL26519222 0.75 DDB1 (0.56) DDB1CRBN
SCHEMBL27167860 0.75 DDB1 (0.67) DDB1CRBN
Hydrochloric Acid SCHEMBL29279132 0.74 DDB1 (0.66) DDB1CRBN
SCHEMBL23594665 0.73 CRBN (0.59) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083194-A1 WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF 杭州格博生物医药有限公司 2023-05-19 WO disclosed