Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975029 | 0.88 | CRBN (0.58) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL30993527 | 0.84 | CRBN (0.57) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL24833731 | 0.84 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL30577952 | 0.84 | CRBN (0.56) | CRBNDDB1IKZF3BRD4PARP1 | |
| SCHEMBL30993110 | 0.84 | CRBN (0.56) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL30577953 | 0.83 | CRBN (0.55) | CRBNDDB1IKZF3BRD4PARP1 | |
| SCHEMBL23799186 | 0.82 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL23812278 | 0.82 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL30992983 | 0.82 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL23561241 | 0.81 | CRBN (0.62) | CRBNDDB1IKZF3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |