SCHEMBL25567645

SCHEMBL25567645

Cc1[nH]c(/C=C2\C(=O)Nc3cc(NC(=O)C4(C(=O)Nc5cc(C(C)(C)C)on5)CC4)ccc32)c(C)c1N

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25564815 0.91 CSF1R (0.82) CSF1R
SCHEMBL25567775 0.90 CSF1R (0.71) CSF1R
SCHEMBL25567495 0.89 CSF1R (0.70) CSF1R
SCHEMBL25567651 0.88 CSF1R (0.71) CSF1R
SCHEMBL25564599 0.83 CSF1R (0.86) CSF1R
SCHEMBL25564594 0.83 CSF1R (0.85) CSF1R
SCHEMBL25171428 0.81 CSF1R (1.00) CSF1R
SCHEMBL25171427 0.81 CSF1R (1.00) CSF1R
SCHEMBL25185186 0.80 CSF1R (1.00) CSF1R
SCHEMBL25181745 0.80 CSF1R (1.00) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078207-A1 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 南京中医药大学 2023-05-11 — — WO disclosed
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