⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25568343 | 1.00 | — | — | |
| SCHEMBL13640412 | 0.83 | PPM1D (0.31) | — | |
| SCHEMBL25568326 | 0.83 | — | — | |
| SCHEMBL25568344 | 0.78 | — | — | |
| SCHEMBL25568341 | 0.78 | — | — | |
| SCHEMBL25568329 | 0.74 | PPM1D (0.34) | — | |
| SCHEMBL28333814 | 0.73 | — | — | |
| SCHEMBL25568332 | 0.73 | MAPT (0.31) | — | |
| SCHEMBL25568333 | 0.73 | MAPT (0.31) | — | |
| SCHEMBL19431538 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159517-A1 | CHROMANE AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | US | disclosed |